Can CBD Oil Get You High?
CBD and THC are both derived from the cannabis plant, but have very different effects on your body and brain.
One of the first questions asked by people just learning about CBD oil is, “Can CBD oil get you high?”
It’s a valid question, and given that there is still a large portion of the general public who consider CBD oil to be little more than marijuana in disguise, it’s essential that in your search for information, you find the right information.
So, for the purposes of this page, we’ll define “high” as meaning a decrease in your mental or physical capabilities.
We’re here to clear up the biggest misconceptions about CBD oil and arm you with the knowledge you need to make the right choices for your personal health and supplement needs.
CBD vs. THC: A Cannabinoid Overview
Cannabidiol (CBD) and tetrahydrocannabinol (THC) are two of hundreds of cannabinoids present in the cannabis plant.
THC is the cannabinoid that occurs in the largest quantity within cannabis, while CBD presents in a much smaller ratio.
Because of CBD oil’s rise in popularity, many growers are now cultivating cannabis plants with high CBD content.
Both cannabinoids are currently being put through intensive studies, although their benefits have only been anecdotally known for some time. Prior to recent changes in legislation that allow for the sale of medical cannabis in a majority of U.S. states, it was difficult, if not impossible to legally conduct research into the potential positives effects of taking CBD oil.
What we do know is that both THC and CBD are the phytocannabinoid (plant) versions of our body’s endocannabinoids (internal). Phytocannabinoids impact our endocannabinoid system, which consists of two main receptors: the CB1, and CB2 receptors, located predominantly in the brain and the central nervous system, respectively. These receptors impact a vast array of functions within the body like pain perception, the experience of anxiety, inflammation, and appetite.
While THC has been shown to directly target and bind to the CB1 and CB2 receptors, CBD instead creates the majority of its therapeutic benefits indirectly, activating both cannabinoid and non-cannabinoid receptors.
Not All Cannabis Plants Are the Same
Cannabis, despite what people think, is not a single plant. In fact, it is a genus in a family of flowering plants. This genus includes both cannabis sativa and cannabis indica. The substance popularly known as marijuana can be of the sativa or indica variety.
Hemp is also a type of sativa plant, however, it has few to none of the intoxicating effects that marijuana sativa plants carry. Biologically, hemp is quite different from marijuana and typically contains much higher levels of CBD and lower levels of THC relative to marijuana.
Historically, hemp has been cultivated for its hard and fibrous qualities, used in the production of items like paper, rope, and cloth. Now, hemp is the primary source of CBD oil.
Marijuana is the type of cannabis that when smoked or ingested, produces psychoactive, intoxicating effects, creating a “high” caused by the THC . THC, through its action on the brain, triggers a dopamine release. This flood of dopamine is the source of positive emotions and the high that is felt by marijuana users. THC also impacts the hypothalamus (appetite), the basal ganglia (cognition and emotion), cerebellum (sensory perception), and the neocortex (perception and conscious thought).
The hemp plant does not produce these results, as CBD does not play the same role in the body. This means CBD oil is not going to get you high in the same way as marijuana. But just because it won’t get you high, doesn’t mean it’s not psychoactive.
Psychoactive vs. Intoxication: What’s the Difference?
CBD oil cannot get you high but it is a psychoactive substance. This concept is a difficult one to unravel, but here’s a breakdown:
An intoxicant is a substance that when taken produces a state of diminished mental and physical ability. Examples of this include alcohol, recreational drugs, and THC.
A psychoactive substance is one that changes an individual’s mental state by impacting how the brain and central nervous system function. Examples include caffeine, chocolate, and CBD.
As you can see, while the “psychoactive” label attached to CBD oil may seem damning at first, understanding the terminology helps to uncover that many psychoactive substances can produce positive results, whereas intoxicants impact the brain in a negative way.
So, CBD oil is a psychoactive substance, but it will not get you high.
Why Choose CBD Oil over Marijuana
When isolated from the cannabis plant, CBD oil is able to be produced containing only trace amounts of THC (<0.3%).
While this process removes some of the potential whole plant benefits that have been linked to THC, it more importantly removes any intoxicating properties, making it an ideal choice for anyone who wishes to remain clear-headed while using CBD oil.
The use of CBD oil alone has been shown to have potential benefits in the treatment of pain, inflammation, insomnia, depression, anxiety, heart disease, and a vast number of other conditions.
Is CBD Oil Right for You?
The decision about whether or not CBD oil is the right treatment option for you will depend on your needs and the laws in your state.
While there is still a great deal of research left to be done, the World Health Organization (WHO) has reported that CBD doesn’t yield the same effects as THC, and could present a slew of therapeutic health benefits without posing much medical risk to those who consume it.
Now that you know that CBD oil is not going to get you high, you can consider it more seriously as an option for treatment. If you’re considering CBD oil, still speak to your doctor so you can make the most informed decision possible. While largely safe to use, CBD oil does interact with a handful of medications, including some common antidepressants, so it is best to seek professional advice.
From there, you can decide if CBD oil could be of benefit to you.
+ 56 sources
O Valverde (2011) CB1 receptor-deficient mice as a model for depression - National Library of Medicine
O Gomez et al. Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways - National Library of Medicine
(2021) Leaky gut syndrome - Wikipedia®
A. Alhamoruni et al. (2010) Pharmacological Effects of Cannabinoids on the Caco-2 Cell Culture Model of Intestinal Permeability - American Society for Pharmacology and Experimental Therapeutics
Grzegorz Godlewski et al. (2004) Presynaptic cannabinoid CB1 receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats - National Center for Biotechnology Information
Matthew N Hill et al. (2013) Translational evidence for the involvement of the endocannabinoid system in stress-related psychiatric illnesses - National Center for Biotechnology Information
(2021) Brain-derived neurotrophic factor - Wikipedia®
(2021) Peroxisome proliferator-activated receptor - Wikipedia®
Huizhi Du et al. Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ - National Library of Medicine
Aymen I. Idris et al. (2012) Role of cannabinoids in the regulation of bone remodeling - National Center for Biotechnology Information
(2021) Prolactin - Wikipedia®
B Y Ho et al. Cannabinoid CB1 receptor-mediated inhibition of prolactin release and signaling mechanisms in GH4C1 cells - National Library of Medicine
(2021) Fatty acid amide hydrolase - Wikipedia®
Luciano De Petrocellis et al. The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation - National Center for Biotechnology Information
Silvana Gaetani et al. Anandamide hydrolysis: a new target for anti-anxiety drugs? - National Library of Medicine
G. Gobbi et al. (2005) Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis - National Center for Biotechnology Information
Bradley E. Alger, Ph.D. (2013) Getting High on the Endocannabinoid System - National Center for Biotechnology Information
R B Laprairie et al. (2015) Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor - National Center for Biotechnology Information
Markus Kathmann et al. (2006) Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors - National Library of Medicine
(2021) 5-HT1A receptor - Wikipedia®
Ethan B Russo et al. Agonistic properties of cannabidiol at 5-HT1a receptors - National Library of Medicine
Haleli Sharir et al. (2010) Pharmacological Characterization of GPR55, A Putative Cannabinoid Receptor - National Center for Biotechnology Information
(2021) TRPV1 - Wikipedia®
(2021) Peroxisome proliferator-activated receptor gamma - Wikipedia®
Huizhi Du et al. Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ - National Library of Medicine
Ethan B Russo Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? - National Library of Medicine
Evan C. Rosenberg et al. (2015) Cannabinoids and Epilepsy - National Center for Biotechnology Information
Thorsten Rudroff et al. (2017) Cannabis and Multiple Sclerosis—The Way Forward - National Center for Biotechnology Information
Sabrina Giacoppo et al. Can cannabinoids be a potential therapeutic tool in amyotrophic lateral sclerosis? - National Center for Biotechnology Information
Mario Stampanoni Bassi et al. (2017) Cannabinoids in Parkinson's Disease - National Center for Biotechnology Information
Prakash Nagarkatti et al. Cannabinoids as novel anti-inflammatory drugs - National Center for Biotechnology Information
Attila Oláh et al. (2014) Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes - National Center for Biotechnology Information
Barbara S. Koppel (2015) Cannabis in the Treatment of Dystonia, Dyskinesias, and Tics - National Center for Biotechnology Information
Jonathan D Wilkinson et al. (2006) Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis - National Library of Medicine
Natalya M Kogan et al. (2015) Cannabidiol, a Major Non-Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts - National Library of Medicine
Sevda Dirikoc et al. Nonpsychoactive cannabidiol prevents prion accumulation and protects neurons against prion toxicity - National Library of Medicine
Alexandre R de Mello Schier et al. Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa - National Library of Medicine
Carol Shoshkes Reiss et al. (2010) Cannabinoids and Viral Infections - National Center for Biotechnology Information
Béla Horváth et al. The Endocannabinoid System and Plant-Derived Cannabinoids in Diabetes and Diabetic Complications - National Center for Biotechnology Information
D.C. Hammell et al. (2015) Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis - National Center for Biotechnology Information
Linda A Parker et al. Regulation of nausea and vomiting by cannabinoids - National Center for Biotechnology Information
Esther M. Blessing et al. (2015) Cannabidiol as a Potential Treatment for Anxiety Disorders - National Center for Biotechnology Information
Ruth E Cooper et al. (2017) Cannabinoids in attention-deficit/hyperactivity disorder: A randomised-controlled trial - National Library of Medicine
Marc W. Manseau et al. (2015) Cannabinoids and Schizophrenia: Risks and Therapeutic Potential - National Center for Biotechnology Information
Mélissa Prud’homme et al. (2015) Cannabidiol as an Intervention for Addictive Behaviors: A Systematic Review of the Evidence - National Center for Biotechnology Information
Christopher P Stanley et al. Is the cardiovascular system a therapeutic target for cannabidiol? - National Library of Medicine
Waseem Ahmed, MD et al. Therapeutic Use of Cannabis in Inflammatory Bowel Disease - National Center for Biotechnology Information
Wei Xiong et al. (2012) Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors - National Center for Biotechnology Information
Anna Maria Malfitano et al. Cannabinoids in the management of spasticity associated with multiple sclerosis - National Center for Biotechnology Information
Kevin P. Hill et al. (2017) Cannabis and Pain: A Clinical Review - National Center for Biotechnology Information
Natalya M. Kogan et al. Cannabinoids in health and disease - National Center for Biotechnology Information
Nora D. Volkow, M.D et al. Adverse Health Effects of Marijuana Use - National Center for Biotechnology Information
Hemant Goyal et al. Role of cannabis in cardiovascular disorders - National Center for Biotechnology Information
Timothy E. Welty, PharmD et al. Cannabidiol: Promise and Pitfalls - National Center for Biotechnology Information
Thomas Insel (2014) Post by Former NIMH Director Thomas Insel: Are Children Overmedicated? - National Institute of Health
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